Remodelin hydrobromide
CAS No. 1622921-15-6
Remodelin hydrobromide ( Remodelin HBr; Remodelin Hydrobromide )
产品货号. M12394 CAS No. 1622921-15-6
A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥421 | 有现货 |
|
10MG | ¥640 | 有现货 |
|
25MG | ¥1199 | 有现货 |
|
50MG | ¥2122 | 有现货 |
|
100MG | ¥3175 | 有现货 |
|
500MG | ¥7177 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Remodelin hydrobromide
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
-
产品描述A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
-
同义词Remodelin HBr; Remodelin Hydrobromide
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体acetyl-transferaseNAT10
-
研究领域Other Indications
-
适应症——
化学信息
-
CAS Number1622921-15-6
-
分子量363.28
-
分子式C15H15BrN4S
-
纯度>98% (HPLC)
-
溶解度DMSO: ≥ 44 mg/mL
-
SMILESN#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br
-
化学全称Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-, hydrobromide (1:1)
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
产品手册
关联产品
-
Detomidine HCl
Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
-
Pimelic Diphenylamid...
A slow, tight-binding inhibitor of class I HDACs.
-
C5-benzyl SAHA
C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.