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Remodelin hydrobromide

CAS No. 1622921-15-6

Remodelin hydrobromide ( Remodelin HBr; Remodelin Hydrobromide )

产品货号. M12394 CAS No. 1622921-15-6

A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥421 有现货
10MG ¥640 有现货
25MG ¥1199 有现货
50MG ¥2122 有现货
100MG ¥3175 有现货
500MG ¥7177 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Remodelin hydrobromide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
  • 产品描述
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
  • 同义词
    Remodelin HBr; Remodelin Hydrobromide
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    acetyl-transferaseNAT10
  • 研究领域
    Other Indications
  • 适应症
    ——

化学信息

  • CAS Number
    1622921-15-6
  • 分子量
    363.28
  • 分子式
    C15H15BrN4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 44 mg/mL
  • SMILES
    N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br
  • 化学全称
    Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-, hydrobromide (1:1)

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
产品手册
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